Predicting T cell specificity using ML and deep phenotypic data

“Can we predict T cell specificity with digital biology and machine learning?” was the title of a recent publication in Nature Reviews Immunology by Hudson et al.. The author’s conclusion was: It’s tough. Why bother in the first place? Because T cells target all sorts of diseases, their receptor sequences... [Read More]

Integrating Azure Batch support in Snakemake

In my two previous posts I showed how to run Snakemake on Azure Kubernetes Service (AKS) without a shared filesystem. While there is nothing wrong with this setup, there is another Azure service that’s actually meant for this type of batch computing scenario: Azure Batch, a cloud based job scheduling... [Read More]

Using Azure Container Registries with Snakemake and AKS

In a previous post I showed how to run Snakemake on an auto-scaling Kubernetes cluster without shared filesystem on Azure. There I used a public Dockerhub repo for the Snakemake container. Since we were running Kubernetes on Azure it makes sense to use Azure Container registries (ACR; which supports Singularity... [Read More]